Mass-directed isolation of the CH 2 Cl 2 /CH 3 OH extract from a marine sponge of the genus Pseudoceratina resulted in the purification of a new antimalarial bromotyrosine alkaloid, psammaplysin H (1), along with the previously isolated analogs psammaplysins G (2) and F (3). The structure of 1 was e
New Pyridinium Alkaloids from a Marine Sponge of the Genus Spongia with a Human Phospholipase A 2 Inhibitor Profile
✍ Scribed by De Marino, Simona; Iorizzi, Maria; Zollo, Franco; Debitus, Cecile; Menou, Jean-Louis; Ospina, Luis Fernando; Alcaraz, María José; Payá, Miguel
- Book ID
- 127299492
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 63 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0163-3864
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A new bioactive sesquiterpenoid, named dysidotronic acid 1, with a rearranged drimane skeleton has been isolated from the sponge Dysidea sp. from Vanuatu islands, along with bolinaquinone 2. The chemical structure of 1 was determined on the basis of spectroscopic data. Dysidotronic acid significantl
## Abstract Mass‐directed isolation of the large‐scale CH~2~Cl~2~/Me‐OH extract from the title sponge affords the new alkaloid psammaplysin H (I) together with the previously isolated analogues psammaplysins G and F.