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New Sesquiterpene Derivatives from the Sponge Dysidea Species with a Selective Inhibitor Profile against Human Phospholipase A 2 and Other Leukocyte Functions

✍ Scribed by Giannini, Clelia; Debitus, Cécile; Lucas, Rut; Ubeda, Amalia; Payá, Miguel; Hooper, John N. A.; D'Auria, Maria Valeria


Book ID
120600378
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
50 KB
Volume
64
Category
Article
ISSN
0163-3864

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Dysidotronic acid, a new and selective h
✍ Clelia Giannini; Cécile Debitus; Inmaculada Posadas; Miguel Payá; Maria Valeria 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 133 KB

A new bioactive sesquiterpenoid, named dysidotronic acid 1, with a rearranged drimane skeleton has been isolated from the sponge Dysidea sp. from Vanuatu islands, along with bolinaquinone 2. The chemical structure of 1 was determined on the basis of spectroscopic data. Dysidotronic acid significantl