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New Methods for the High-Throughput Screening of Enantioselective Catalysts and Biocatalysts

โœ Scribed by Manfred T. Reetz

Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
196 KB
Volume
41
Category
Article
ISSN
0044-8249

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๐Ÿ“œ SIMILAR VOLUMES

A Method for High-Throughput Screening o
A Method for High-Throughput Screening of Enantioselective Catalysts
โœ Manfred T. Reetz; Michael H. Becker; Heinz-Werner Klein; Detlef Stรถckigt ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 119 KB ๐Ÿ‘ 1 views

About 1000 catalytic or stoichiometric asymmetric reactions of racemic compounds or prochiral substrates bearing enantiotopic groups can be analyzed per day. In this highly efficient method the enantioselectivity is determined by electrospray ionization mass spectrometry using isotopically labeled s

A Practical NMR-Based High-Throughput As
A Practical NMR-Based High-Throughput Assay for Screening Enantioselective Catalysts and Biocatalysts
โœ Manfredโ€…T. Reetz; Andreas Eipper; Patrick Tielmann; Richard Mynott ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 148 KB ๐Ÿ‘ 1 views

Two NMR-based approaches for highthroughput screening of enantioselective catalysts and biocatalysts are described. One version makes use of pseudo-enantiomers or pseudo-meso-compounds based on 13 C-labeling. A throughput of at least 1400 ee determinations per day is possible by using an appropriate