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New and Highly Efficient Synthesis of Cis - and Trans -Opened Benzo[ a ]pyrene 7,8-Diol 9,10-Epoxide Adducts at the Exocyclic N 2 -Amino Group of Deoxyguanosine

✍ Scribed by Kroth, Heiko; Yagi, Haruhiko; Seidel, Albrecht; Jerina, Donald M.


Book ID
126799256
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
121 KB
Volume
65
Category
Article
ISSN
0022-3263

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ChemInform Abstract: New and Highly Effi
✍ Heiko Kroth; Haruhiko Yagi; Albrecht Seidel; Donald M. Jerina πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons βš– 35 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Novel trifluoroethanol mediated synthesi
✍ Andagar R Ramesha; Heiko Kroth; Donald M Jerina πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 74 KB

The exocyclic amino groups of deoxyadenosine and deoxyguanosine readily add to C-10 of the benzo[a]pyrene 7,8-diol 9,10-epoxides at room temperature overnight in trifluoroethanol. Whereas the dG adducts are obtained as a mixture of cis-and trans-opened diastereomers, the dA adducts arise exclusively