The exocyclic amino groups of deoxyadenosine and deoxyguanosine readily add to C-10 of the benzo[a]pyrene 7,8-diol 9,10-epoxides at room temperature overnight in trifluoroethanol. Whereas the dG adducts are obtained as a mixture of cis-and trans-opened diastereomers, the dA adducts arise exclusively
β¦ LIBER β¦
Solvent-Free Synthesis of Benzo[ a ]pyrene 7,8-Diol 9,10-Epoxide Adducts at the N 2 -Position of Deoxyguanosine
β Scribed by Ramesha, Andagar R.; Kroth, Heiko; Jerina, Donald M.
- Book ID
- 126952018
- Publisher
- American Chemical Society
- Year
- 2001
- Tongue
- English
- Weight
- 44 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1523-7060
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