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Nerve growth factor activation of the p-38 apoptotic pathway in p-75 transfected SK-N-SH neuroblastoma cells

✍ Scribed by Janette L. Holub; Yi-Yong Qiu; Mary Beth Madonna


Book ID
113679347
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
112 KB
Volume
209
Category
Article
ISSN
1072-7515

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## Abstract The aim of the present study is to elucidate the signaling pathway involved in death of human neuroblastoma SK‐N‐SH cells induced by __Naja naja atra__ phospholipase A~2~ (PLA~2~). Upon exposure to PLA~2~, p38 MAPK activation, ERK inactivation, ROS generation, increase in intracellular