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Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells

✍ Scribed by Chaohua Yan; Zeljka Korade Mirnics; Carmel F. Portugal; Ye Liang; Karen D. Nylander; Marcelo Rudzinski; Clara Zaccaro; H. Uri Saragovi; Nina Felice Schor

Book ID
116753385
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
390 KB
Volume
139
Category
Article
ISSN
0169-328X

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Role of low-affinity p75 receptor in ner
Role of low-affinity p75 receptor in nerve growth factor-inducible growth arrest of PC12 cells
✍ Hisanori Ito; Hiroshi Nomoto; Shoei Furukawa πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 567 KB

Mutant PC12 cell clones (PC84 cells) were obtained by transfection with nerve growth factor (NGF) cDNA. These cells secreted active NGF, extended short processes, and proliferated faster than the parental PC12 cells. These features are of great interest because the parental PC12 cells cease prolifer