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p38 MAPK as a negative regulator of VEGF/VEGFR2 signaling pathway in serum deprived human SK-N-SH neuroblastoma cells

โœ Scribed by Evan Gomes; Patricia Rockwell


Book ID
116770051
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
466 KB
Volume
431
Category
Article
ISSN
0304-3940

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## Abstract The aim of the present study is to elucidate the signaling pathway involved in death of human neuroblastoma SKโ€Nโ€SH cells induced by __Naja naja atra__ phospholipase A~2~ (PLA~2~). Upon exposure to PLA~2~, p38 MAPK activation, ERK inactivation, ROS generation, increase in intracellular