N -Nitrosation of Myosmine Yields HPB (4-Hydroxy-1-(3-pyridyl)-1-butanone) and NNN ( N -Nitrosonornicotine)
โ Scribed by Zwickenpflug, Wolfgang
- Book ID
- 127272416
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 47 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0021-8561
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๐ SIMILAR VOLUMES
## The genotoxic potentials of N-nitrosoheptamethyleneimine (NHMI), 4-(methylnitrosamino)-l-(3-p yridyl)-l-butanone (NNK) and N'-nitrosonornicotine (NNN) were studied in fresh preparations of Clara cells and type H cells isolated by centrifugal elutriation and density gradient centrifugation, and
The carcinogenic tobacco-specif ic nitrosamines 4- (methylnitrosemino) -1-(3-pyridyl) -1-butanone (NNK) and N'-nitrosonornicotine (NNN), as well as the model compound 4-(carbethoxynitrosamino) -1-(3-pyridyl) -1butanone, were synthesized with tritium at the 5-position of the pyridine ring. In each c
An improved high-performance liquid chromatographic system was developed for separation of 11 metabolites of the nicotine-derived nitrosamines N'-nitrosonornicotine (NNN) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). The new system employed a 5-microns octadecylsilane bonded column elute