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N, N-Bis (2-Oxo-3-Oxazolidinyl) Phosphordiamidic Chloride (CLSPO) : A New Strategy for the Ester Function Preparation

✍ Scribed by Ballester-Rodés, M.; Palomo-coll, A. L.


Book ID
126559276
Publisher
Taylor and Francis Group
Year
1984
Tongue
English
Weight
229 KB
Volume
14
Category
Article
ISSN
0039-7911

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N,N-bis[2-oxo-3-oxazolidinyl]phosphorodi
✍ S.B. Katti; K.L. Agarwal 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 190 KB

Use of a rwel ccupliw reagent, N,N-bi$2-oxo-3-oxazolidinyllphosphorcdiamidic chloride (BUPCC) in the synthesis of oligc&.oxy~-ibonucleotides is described. This reagent allm the synthesis of phosphotriesters in high yields (70-m) without detectable side reactions. Synthesis of a hexanucleotide, d(A-A