𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mutational Analyses of Multiple Target Genes in Histologically Heterogeneous Gastric Cancer with Microsatellite Instability

✍ Scribed by Wang, Ying ;Shinmura, Kazuya ;Guo, Rong-Jun ;Isogaki, Jun ;Wang, Dong-Yu ;Kino, Isamu ;Sugimura, Haruhiko

Book ID
108581548
Publisher
Wiley (Blackwell Publishing)
Year
1998
Tongue
English
Weight
681 KB
Volume
89
Category
Article
ISSN
0910-5050

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Mutations of BRAF and KRAS in gastric ca
Mutations of BRAF and KRAS in gastric cancer and their association with microsatellite instability
✍ Wei Zhao; Tsun Leung Chan; Kent-Man Chu; Annie S. Chan; Michael R. Stratton; Siu πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 French βš– 53 KB πŸ‘ 1 views

## Dear Sir, The RAS proteins participate in the RAS-RAF-MEK-ERK-MAPKinase pathway, which mediates cellular responses to growth signals. 1 There are 3 RAF genes, each encoding cytoplasmic serine/threonine kinases that are regulated by binding to RAS. 1,2 We have recently reported that BRAF is soma

Influence of target gene mutations on su
Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers
✍ Barbara Jung; E. Julieta Smith; Ryan T. Doctolero; Pascal Gervaz; Julio C. Alons πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 French βš– 89 KB

## Abstract High‐frequency microsatellite unstable (MSI‐H) colon tumors develop as a consequence of mutations at repetitive sequences in target genes. __TGFBR2__ and __ACVR2__, encoding TGFΞ² superfamily receptors, and the proapoptotic gene __BAX__ are frequent targets for frameshift mutation. We an