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Mutational and expressional analysis of cathepsin D in gastric and colorectal cancers with microsatellite instability

โœ Scribed by YOO RI KIM; HO SHIK KIM; CHANG HYEOK AN; NAM JIN YOO; SUG HYUNG LEE

Book ID
109344069
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
280 KB
Volume
118
Category
Article
ISSN
0365-5555

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## Dear Sir, The RAS proteins participate in the RAS-RAF-MEK-ERK-MAPKinase pathway, which mediates cellular responses to growth signals. 1 There are 3 RAF genes, each encoding cytoplasmic serine/threonine kinases that are regulated by binding to RAS. 1,2 We have recently reported that BRAF is soma