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Mutation screening ofRAD51Cin high-risk breast and ovarian cancer families

✍ Scribed by Wenping Lu,Xianshu Wang,Hongsheng Lin,Noralane M. Lindor…


Book ID
126355394
Publisher
Springer Netherlands
Year
2012
Tongue
English
Weight
187 KB
Volume
11
Category
Article
ISSN
1389-9600

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There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the prevalence of such mutations, and whether they are associated with a particular clinical phenotype, remains unclear. Resolving these questions has important implications