The role of Jak3 in lymphoid development
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Daniel C Thomis; Leslie J Berg
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Article
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1997
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Elsevier Science
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English
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Mutations in a number of lymphoid signaling molecules lead to immunodeficiencies in mice and humans. Among these, one very pleiotropic syndrome results from deficiencies in an array of cytokine signaling pathways utilizing a cytokine receptor common y chain, Yo and the tyrosine kinase Jak3. Recent a