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Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID)

โœ Scribed by P. Macchi


Book ID
117756776
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
109 KB
Volume
1
Category
Article
ISSN
1357-4310

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Mutations in severe combined immune defi
โœ Luigi D. Notarangelo; Patrizia Mella; Alison Jones; Genevieve de Saint Basile; G ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 407 KB

During the last 10 years, an increasing number of genes have been identified whose abnormalities account for primary immunodeficiencies, with defects in development and/or function of the immune system. Among them is the JAK3-gene, encoding for a tyrosine kinase that is functionally coupled to cytok