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Mutation induction in Chinese hamster lung V79 cells by five alk-2-enals produced by lipid peroxidation

โœ Scribed by Roberta Canonero; Antonietta Martelli; Umberto M. Marinari; Giovanni Brambilla


Book ID
113255366
Publisher
Elsevier Science
Year
1990
Weight
274 KB
Volume
244
Category
Article
ISSN
0165-7992

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Mutation induction in chinese hamster V7
โœ Eliezer Huberman; Helmut Bartsch; Leo Sachs ๐Ÿ“‚ Article ๐Ÿ“… 1975 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 421 KB

## Abstract Chloroethylene oxide and 2โ€chloroacetaldehyde, two possibly carcinogenic metabolites of vinyl chloride in mammals, caused a doseโ€dependent induction of 8โ€azaguanineโ€and ouabainโ€resistant mutants in Chinese hamster V79 cells in vitro. Up to oneโ€hundredfold higher concentrations of 2โ€chlo