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Mutation induction by aromatic amines in V79 Chinese hamster cells

โœ Scribed by G. Fassina; A. Abbondandolo; S. Parodi


Book ID
113251149
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
169 KB
Volume
147
Category
Article
ISSN
0165-1161

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## Abstract Chloroethylene oxide and 2โ€chloroacetaldehyde, two possibly carcinogenic metabolites of vinyl chloride in mammals, caused a doseโ€dependent induction of 8โ€azaguanineโ€and ouabainโ€resistant mutants in Chinese hamster V79 cells in vitro. Up to oneโ€hundredfold higher concentrations of 2โ€chlo