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Induction of mutation in V79 Chinese hamster cells by tetrachlorohydroquinone, a metabolite of pentachlorophenol

โœ Scribed by Kristian Jansson; Vuokko Jansson


Book ID
119093566
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
333 KB
Volume
260
Category
Article
ISSN
0165-1218

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## Abstract Chloroethylene oxide and 2โ€chloroacetaldehyde, two possibly carcinogenic metabolites of vinyl chloride in mammals, caused a doseโ€dependent induction of 8โ€azaguanineโ€and ouabainโ€resistant mutants in Chinese hamster V79 cells in vitro. Up to oneโ€hundredfold higher concentrations of 2โ€chlo