𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Mutation analysis of presenilin 1 gene in Alzheimer's disease

✍ Scribed by BOTEVA, K


Book ID
122915215
Publisher
The Lancet
Year
1996
Tongue
English
Weight
466 KB
Volume
347
Category
Article
ISSN
0140-6736

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Presenilin-1 mutations in Alzheimer's di
✍ Gambetti, P.; Russo, C.; Schettini, G.; Saido, T. C.; Hulette, C.; Lippa, C.; La πŸ“‚ Article πŸ“… 2000 πŸ› Nature Publishing Group 🌐 English βš– 258 KB
Presenilin mutations in Alzheimer's dise
✍ Marc Cruts; Christine Van Broeckhoven πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 212 KB πŸ‘ 2 views

The presenilins (PS-1 and PS-2) are 2 members of a novel family of genes encoding integral membrane proteins recently implicated in Alzheimer's disease (AD) pathology. To date, 43 mutations have been identified in PS-1 and 2 in PS-2 that lead to familial presenile AD (onset before age 65 years). The

Missense mutations in the chromosome 14
✍ Parvoneh Poorkaj; Vikram Sharma; Leojean Anderson; Ellen Nemens; Ma Elias Alonso πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 156 KB πŸ‘ 2 views

Mutations in the presenilin genes (PS-1 and PS-2) cause early onset autosomal dominant Alzheimer's disease (AD). Eight early-onset, autopsy-documented familial AD kindreds were screened for mutations in PS-1, and seven different mutations were identified. Three of these were new mutations (G209V, A4