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Mutagenicity of nitrophenanthrene derivatives for Salmonella typhimurium: effects of nitroreductase and acetyltransferase

✍ Scribed by Nobuyuki Sera; Kiyoshi Fukuhara; Naoki Miyata; Hiroshi Tokiwa

Book ID: 113194846
Publisher: Elsevier Science
Year: 1996
Tongue: English
Weight: 720 KB
Volume: 349
Category: Article
ISSN: 0027-5107
DOI: 10.1016/0027-5107(95)00173-5

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## Abstract A highly sensitive __umu__ test system for the detection of genotoxic activities of a variety of mutagenic nitroarenes has been developed using a new tester strain, __Salmonella typhimurium__ NM3009 having high O‐acetyltransferase (O‐AT) and nitroreductase (NR) activities. The NM3009 wa