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Cloning of Salmonella typhimurium genes for nitroreductase and acetyltransferase, enzymes known to activate some nitroarenes

✍ Scribed by M. Watanabe; T. Nohmi; M. Ishidate Jr.

Book ID: 113251502
Publisher: Elsevier Science
Year: 1987
Tongue: English
Weight: 83 KB
Volume: 182
Category: Article
ISSN: 0165-1161
DOI: 10.1016/0165-1161(87)90146-4

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## Abstract A highly sensitive __umu__ test system for the detection of genotoxic activities of a variety of mutagenic nitroarenes has been developed using a new tester strain, __Salmonella typhimurium__ NM3009 having high O‐acetyltransferase (O‐AT) and nitroreductase (NR) activities. The NM3009 wa