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Cloning of Salmonella typhimurium genes for nitroreductase and acetyltransferase: construction of Salmonella highly sensitive to mutagenic nitroarenes

✍ Scribed by M. Watanabe; T. Nohmi; M. Ishidate Jr.

Book ID
113251594
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
84 KB
Volume
203
Category
Article
ISSN
0165-1161

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## Abstract A highly sensitive __umu__ test system for the detection of genotoxic activities of a variety of mutagenic nitroarenes has been developed using a new tester strain, __Salmonella typhimurium__ NM3009 having high O‐acetyltransferase (O‐AT) and nitroreductase (NR) activities. The NM3009 wa