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Influence of nitroreductase and O-acetyltransferase on the mutagenicity of substituted nitrobenzothiophenamines in Salmonella typhimurium

✍ Scribed by Patrizia Hrelia; Carmela Fimognari; Francesca Maffei; Domenico Spinelli; Liliana Lamartina; Maria Concetta Sarvà; Giorgio Cantelli Forti


Book ID
114009678
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
91 KB
Volume
118
Category
Article
ISSN
0009-2797

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Highly sensitive umu test system for the
✍ Dr. Yoshimitsu Oda; Hiroshi Yamazaki; Mosahiko Watanabe; Takehiko Nohmi; Tsutomu 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 717 KB

## Abstract A highly sensitive __umu__ test system for the detection of genotoxic activities of a variety of mutagenic nitroarenes has been developed using a new tester strain, __Salmonella typhimurium__ NM3009 having high O‐acetyltransferase (O‐AT) and nitroreductase (NR) activities. The NM3009 wa