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Mutagenicity of mono-, di- and tri-nitropyrenes in Chinese hamster ovary cells

โœ Scribed by A.P. Li; J.S. Dutcher

Book ID
113254490
Publisher
Elsevier Science
Year
1983
Weight
265 KB
Volume
119
Category
Article
ISSN
0165-7992

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A strong teratogen-6-aminonicotinamide (6-AN)-was tested for its ability to induce cytotoxicity and mutagenicity in Chinese hamster ovary (CHO) cells. Tests were performed in the presence and absence of a metabolic activation system (S-9 mix). Cytotoxicity was evaluated in CHO cells by the total pro