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Comparative mutagenicity of alkylsulfate and alkanesulfonate derivatives in chinese hamster ovary cells

โœ Scribed by David B. Couch; Nancy L. Forbes; Abraham W. Hsie


Book ID
113191491
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
508 KB
Volume
57
Category
Article
ISSN
0027-5107

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A strong teratogen-6-aminonicotinamide (6-AN)-was tested for its ability to induce cytotoxicity and mutagenicity in Chinese hamster ovary (CHO) cells. Tests were performed in the presence and absence of a metabolic activation system (S-9 mix). Cytotoxicity was evaluated in CHO cells by the total pro