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Multiple alpha-synuclein gene polymorphisms are associated with Parkinson’s disease in a Norwegian population

✍ Scribed by R. Myhre; M. Toft; J. Kachergus; M. M. Hulihan; J. O. Aasly; H. Klungland; M. J. Farrer

Book ID
109338788
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
226 KB
Volume
118
Category
Article
ISSN
0001-6314

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## Abstract Alpha‐synuclein gene (__SNCA__) mutations cause familial Parkinsonism but the role of __SNCA__ variability in idiopathic Parkinson's disease (PD) remains incompletely defined. We report a study of __SNCA__ genetic variation in 452 idiopathic PD cases and 245 controls. __SNCA__ copy numb