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PARKIN-coding polymorphisms are not associated with Parkinson's disease in a population from northeastern Mexico

✍ Scribed by Héctor R. Martínez; Humberto González-González; Leonel Cantú-Martínez; Ricardo Rangel-Guerra; Carlos D. Hernández-Castillo; Juan J.J. Vergara-Saavedra; Martin R. Ramos-Gonzalez; Ricardo M. Cerda-Flores; Marco A. Morales-Garza; Marcos J. Guerrero-Muñoz; Roberto Montes-de-Oca-Luna; Odila Saucedo-Cárdenas


Book ID
116771867
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
126 KB
Volume
468
Category
Article
ISSN
0304-3940

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## Abstract Alpha‐synuclein gene (__SNCA__) mutations cause familial Parkinsonism but the role of __SNCA__ variability in idiopathic Parkinson's disease (PD) remains incompletely defined. We report a study of __SNCA__ genetic variation in 452 idiopathic PD cases and 245 controls. __SNCA__ copy numb