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Multicomponent One-pot Diastereoselective Synthesis of Biologically Important Scaffold under Microwaves

โœ Scribed by Anshu Dandia; Ruby Singh; Pritima Sarawgi; Sarita Khaturia


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
49 KB
Volume
24
Category
Article
ISSN
0256-7660

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โœฆ Synopsis


Abstract

A simple and fast threeโ€component diastereoselective synthesis of biologically important spiro scaffold 4 was carried out in reasonable purity starting from readily available 1__H__โ€indoleโ€2,3โ€dione 1, ethyl cyanoacetate 2 and 4โ€hydroxycoumarin 3 under microwave in high yield (88%โ€“92%) and short time.


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