Motor neuropathy with activity of monoclonal IgM antibody to GD1a ganglioside
β Scribed by E. Bollensen; H. I. Schipper; A. J. Steck
- Publisher
- Springer
- Year
- 1989
- Tongue
- English
- Weight
- 302 KB
- Volume
- 236
- Category
- Article
- ISSN
- 0340-5354
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π SIMILAR VOLUMES
We describe a 52-year-old man who had an acute-onset purely motor neuropathy fulfilling the diagnostic criteria for the Guillain-BarrΓ© syndrome, in whom virtually complete spontaneous recovery occurred by 1 year, and in whom high titres of polyclonal serum antibody to GM1, GD1b, asialo-GM1 and lacto
Immunoglobulin M (IgM) M-protein in sera from patients with peripheral neuropathy frequently binds to glycoconjugates. The sulfated glucuronyl residue shared by myelin-associated glycoprotein (MAG) and sulfated glucuronyl glycolipids (SGGLs) is the epitope most frequently recognized. The IgM M-prote