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Monosomy 3 and trisomy 8: Recurrent chromosomal abnormalities associated with uveal melanoma

✍ Scribed by DE Horsman; VA White


Book ID
119105101
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
62 KB
Volume
56
Category
Article
ISSN
0165-4608

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Non-random abnormalities of chromosomes
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Posterior uveal melanomas have nonrandom alterations affecting chromosomes 3, 6, and 8. Loss of chromosome 3 in uveal melanoma has been shown to act as a predictor of disease-free and overall survival. To confirm the significance of chromosome 3 loss and to extend the observations to include those o