𝔖 Bobbio Scriptorium
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Monoclonal antibodies labeled with polymeric paramagnetic ion chelates

✍ Scribed by Paul Shreve; Alex M. Aisen

Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
331 KB
Volume
3
Category
Article
ISSN
0740-3194

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✦ Synopsis

Polymeric paramagnetic ion chelate molecules were synthesized and covalently linked to monoclonal antibodies. The labeled antibodies retained their antigen binding capacity in vitro while carrying up to an average of 50 paramagnetic ion chelates, enabling specifically bound antibody concentrations less than 2.0 pM to significantly reduce proton longitudinal relaxation times. o 1986 Academic press. Inc.

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