## Abstract The present study refers to the preparation of a 99m‐Technetium labelled murine monoclonal antibody for clinical application. The monoclonal antibody was incubated with a 20fold molar excess of 2‐iminothiolane. The free thiol groups created, were capable of binding reduced technetium. L
✦ LIBER ✦
99mTc Labeled Biotin Conjugate in a Tumor “Pretargeting” Approach with Monoclonal Antibodies
✍ Scribed by Dipl.-Chem. Peter Koch; Prof. Dr. Helmut Robert Mäcke
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 357 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0044-8249
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Objective. To compare the incidence of antidouble-stranded DNA (anti-dsDNA) antibodies in rheumatoid arthritis (RA) patients receiving either single or multiple doses of a chimeric anti-tumor necrosis factor ␣ (anti-TNF␣) antibody or placebo infusions, with or without methotrexate, in open-label, ra