Molecules involved in T-cell costimulation
β Scribed by Marc K. Jenkins; Julia G. Johnson
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 912 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
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The specificity of T-cell recognition is dictated by the interaction of the T-cell receptor with MHC-peptide complexes. The biological consequences of such recognition is determined, however, by costimulatory pathway(s). Recent studies have led to the identification of receptor-counter-receptor pair
Over the past decade there have been many attempts to identify the molecules that serve as ligands in cell-cell adhesion. In general, these studies have focused on a search for substances endogenous to a tissue that can either enhance or inhibit aggregation directly and that either demonstrate tissu