Multicellularity in the cellular slime mold Dictyostelium discoideum is achieved by the expression of two types of cell-cell adhesion sites. The EDTA-sensitive adhesion sites are expressed very early in the developmental cycle and a surface glycoprotein of 24000Da is known to be responsible for thes
Molecules involved in cell-cell adhesion during development
β Scribed by Edelman, Gerald M. ;Rutishauser, Urs
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1981
- Tongue
- English
- Weight
- 731 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0275-3723
No coin nor oath required. For personal study only.
β¦ Synopsis
Over the past decade there have been many attempts to identify the molecules that serve as ligands in cell-cell adhesion. In general, these studies have focused on a search for substances endogenous to a tissue that can either enhance or inhibit aggregation directly and that either demonstrate tissue specificity or are present in concentration gradients. Although in many instances the same cell types have been studied, there has been scant agreement on the molecular basis of cell-cell binding.
π SIMILAR VOLUMES
## Abstract __C__lass Iβ__r__estricted __T__ cell __a__ssociated __m__olecule (CRTAM) is a member of the immunoglobulin superfamily that complies with the structural characteristics of the JAM family of proteins and is phylogenetically more closely related to nectinβlike proteins. Here we demonstra
The means by which leukocytes, including lymphocytes, monocytes, and neutrophils, migrate from the circulation to sites of acute and chronic inflammation is an area of intense research interest. Although a number of soluble mediators of these important cellular interactions have been identified, a m
In the mature nervous system adhesion molecules appear to play a rather static role, maintaining synaptic connections, cell-cell contacts and stabilizing neuron-glial interactions. In contrast, during development and learning, adhesive mechanisms are dynamically regulated both spatially and temporal
## Abstract __Background.__ Dynamic changes in cell adhesion and migration are fundamental properties of the cells that are important in hemostasis, vascularization, and wound repair. Changes in cell adhesion and migration are very important in the formation of tumors, and invasion and metastasis b
## Background and objective: Peritoneal dissemination and hepatic metastasis commonly occur after patients with pancreatic cancer have undergone surgery. it is thought that specific adhesion molecules play corresponding roles in cancer metastasis. ## Study design/materials and methods: We conduct