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Molecular dissection of the 11S REG (PA28) proteasome activators

✍ Scribed by Jun Li; Martin Rechsteiner


Book ID
117456579
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
398 KB
Volume
83
Category
Article
ISSN
0300-9084

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The proteasome 11S regulator subunit REG
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Activity of the 20S proteasome, which performs much of the cytosolic and nuclear proteolysis in eukaryotic cells, is controlled by regulatory complexes that bind to one or both ends of the cylindrical proteasome. One of these complexes, the 11S regulator (REG), is a complex of 28 kDa subunits that i