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Modulators of the activation of the proteasome by PA28 (11S Reg)

✍ Scribed by Sherwin Wilk; Wei-Er Chen; Ronald P. Magnusson

Book ID
110244544
Publisher
Springer
Year
1999
Tongue
English
Weight
85 KB
Volume
26
Category
Article
ISSN
0301-4851

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Activity of the 20S proteasome, which performs much of the cytosolic and nuclear proteolysis in eukaryotic cells, is controlled by regulatory complexes that bind to one or both ends of the cylindrical proteasome. One of these complexes, the 11S regulator (REG), is a complex of 28 kDa subunits that i