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Proteasome Activator 11S REG or PA28: Recombinant REGα/REGβ Hetero-oligomers Are Heptamers 1

✍ Scribed by Zhang, Zhiguo; Krutchinsky, Andrew; Endicott, Scott; Realini, Claudio; Rechsteiner, Martin; Standing, Kenneth G.


Book ID
126849737
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
93 KB
Volume
38
Category
Article
ISSN
0006-2960

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Activity of the 20S proteasome, which performs much of the cytosolic and nuclear proteolysis in eukaryotic cells, is controlled by regulatory complexes that bind to one or both ends of the cylindrical proteasome. One of these complexes, the 11S regulator (REG), is a complex of 28 kDa subunits that i