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Molecular cytogenetic characterization of a complex rearrangement involving chromosomes 9 and 22 in a case of Ph-negative chronic myeloid leukemia

✍ Scribed by Clelia Tiziana Storlazzi; Luisa Anelli; Cecilia Surace; Angelo Lonoce; Antonella Zagaria; Mauro Nanni; Paola Curzi; Mariano Rocchi


Book ID
114135340
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
217 KB
Volume
136
Category
Article
ISSN
0165-4608

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W e performed molecular studies to resolve the status of BCR and ABL in the bone marrow cells of a CML patient with a Ph chromosome resulting from a complex translocation involving chromosomes 9, 15, and 22. D N A digestion with BomHI, Hindlll, and Bglll, followed by hybridization to a bcr-specific