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A complex variant Philadelphia (Ph1) chromosome translocation involving chromosomes No. 11, 14, and 22 in a case of chronic myelogenous leukemia

✍ Scribed by Jonathan E. Kolitz; Philip Schulman; Nataline Kardon; Daniel R. Budman; Vincent P. Vinciguerra; Afina Broekman; Thomas J. Degnan


Book ID
119102569
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
222 KB
Volume
4
Category
Article
ISSN
0165-4608

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Molecular confirmation of BCR-ABL fusion
✍ Sugandhi A. Tharapel; Cindy L. Vnencak-Jones; James A. Whitlock; Rajiv Jain πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 274 KB

W e performed molecular studies to resolve the status of BCR and ABL in the bone marrow cells of a CML patient with a Ph chromosome resulting from a complex translocation involving chromosomes 9, 15, and 22. D N A digestion with BomHI, Hindlll, and Bglll, followed by hybridization to a bcr-specific