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Unusual translocations involving chromosomes 12;22 and 9;12 in a case of chronic myelogenous leukemia

✍ Scribed by Sundari Chemitiganti; Ram S. Verma; Richard T. Silver; Morton Coleman; Harvey Dosik


Book ID
119103106
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
358 KB
Volume
14
Category
Article
ISSN
0165-4608

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A 46-year-old man with chronic myelocytic leukemia had a new variant translocation between chromosome 22 and chromosome 7 in bone marrow cells. No involvement of chromosome 9 was seen. The patient entered blastic transformation within half a year, by which time he had acquired an isochromosome 17 in