𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Molecular analysis of the INK4A and INK4B gene loci in human breast cancer cell lines and primary carcinomas

✍ Scribed by Maria Bisogna; Jacqueline E. Calvano; Gay Hui Ho; Irene Orlow; Carlos Cordón-Cardó; Patrick I. Borgen; Kimberly J. Van Zee

Book ID
114134991
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
777 KB
Volume
125
Category
Article
ISSN
0165-4608

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Genetic and epigenetic alterations of th
Genetic and epigenetic alterations of the cyclin-dependent kinase inhibitors p15INK4b and p16INK4a in human thyroid carcinoma cell lines and primary thyroid carcinomas
✍ Rossella Elisei; Masaaki Shiohara; H. Phillip Koeffler; James A. Fagin 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB 👁 2 views

## Background: D-type cyclins, in association with the cyclin-dependent kinases cdk4 and cdk6, promote progression through the g1 phase of the cell cycle. cdk activity is modulated by inhibitors such as p15ink4b and p16ink4a. loss of function of p15ink4b and p16ink4a (multiple tumor suppressor-i an

Molecular analysis of the cyclin-depende
Molecular analysis of the cyclin-dependent kinase inhibitor genes p15INK4b/MTS21, p16INK4/MTS1, p18 and pl9 in human cancer cell lines
✍ Akihiko Gemma; Seiichi Takenoshita; Koichi Hagiwara; Aikou Okamoto; Elisa A. Spi 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 660 KB

Cyclin-dependent kinillre-4 inhibitor genes (INK4) regulate the cell cycle and are candidate tumor-suppressor genes. To determine if alterations in the coding regions of the p18 and p l 9 genes, which are novel members of the INK4 family and if they correlate with the development of human cancer, 10

Intragenic mutations of the p16INK4, p15
Intragenic mutations of the p16INK4, p15INK4B and p18 genes in primary non-small-cell lung cancers
✍ Marek R. Rusin; Aikou Okamoto; Mieczyslaw Chorazy; Kazimierz Czyzewski; Jolanta 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 French ⚖ 721 KB

The p p ! 6INK4 and p I8 genes are members of the gene famil coding for inhibitors of cyclin-dependent kinases 4 and 6. frequently deleted in many human neoplasms. To examine the role of these 3 genes in lung carcinogenesis, somatic mutations within the genes were analyzed by single-strand conformat