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Modulation of human ether-à-go-go-related K+ (HERG) channel inactivation by Cs+ and K+

✍ Scribed by Shetuan Zhang; Steven J. Kehl; David Fedida


Book ID
111120116
Publisher
Cambridge University Press
Year
2003
Tongue
English
Weight
356 KB
Volume
548
Category
Article
ISSN
0022-3751

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Effects of phosphodiesterase (PDE) inhib
✍ Kiyokazu Yunomae; Satoko Ichisaki; Junko Matsuo; Shinichi Nagayama; Koichiro Fuk 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 328 KB

## Abstract It is presumed that phosphodiesterase (PDE) inhibitors have two mechanisms for inhibition of hERG currents in the acute applications to cells: direct channel block, and downregulation of human ether‐a‐go‐go related gene (hERG) activities by PKA‐dependent pathway mediated phosphorylation