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Modulation of breast cancer resistance protein (BCRP/ABCG2) by non-basic chalcone analogues

✍ Scribed by Yi Han; Meliana Riwanto; Mei-Lin Go; Pui Lai Rachel Ee

Book ID
113592071
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
790 KB
Volume
35
Category
Article
ISSN
0928-0987

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## Abstract Breast cancer resistance protein (BCRP/ABCG2) of an ATP‐binding cassette half‐transporter confers resistance against mitoxantrone and camptothecin derivatives of topotecan and irinotecan. Novobiocin, a coumermycin antibiotic, is known to enhance anticancer drug sensitivity of cancer cel