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Modulation of benzo[a]pyrene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism

✍ Scribed by Rojas, M.

Book ID
125853013
Publisher
Oxford University Press
Year
2000
Tongue
English
Weight
98 KB
Volume
21
Category
Article
ISSN
0143-3334

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✍ Dorota Butkiewicz; Ewa Grzybowska; David H. Phillips; Kari Hemminki; MieczysΕ‚aw πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 77 KB πŸ‘ 2 views

Glutathione S-transferases (GSTs) are an important part of the protection system against a wide range of potentially harmful chemical compounds. GSTP1 and GSTM1 are mainly involved in detoxification reactions of PAH carcinogenic intermediates produced by cytochrome P450 (CYP). Polymorphism of the GS