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MLL insertion with MLL-MLLT3 gene fusion in acute leukemia: case report and review of the literature

✍ Scribed by Gwendoline Soler; Isabelle Radford; Claus Meyer; Rolf Marschalek; Chantal Brouzes; David Ghez; Serge Romana; Roland Berger

Book ID
113513318
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
311 KB
Volume
183
Category
Article
ISSN
0165-4608

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## Abstract The formation of a leukemogenic fusion product in hematopoietic malignancies is commonly achieved by chromosomal translocation. Alternate and cytogenetically undetectable mechanisms of fusion transcript generation have been documented for __BCR__–__AB1__, __AML1__–__ETO__, __PML__–__RAR