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A second case of secondary acute myeloblastic leukemia associated with the MLL–KIAA0284 fusion gene

✍ Scribed by Etienne De Braekeleer; Jean-Christophe Ianotto; Nathalie Douet-Guilbert; Claus Meyer; Frédéric Morel; Marie-Josée Le Bris; Rolf Marschalek; Christian Berthou; Claude Férec; Marc De Braekeleer

Book ID
116304654
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
261 KB
Volume
42
Category
Article
ISSN
1079-9796

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Identification of a novel fusion gene ML
Identification of a novel fusion gene MLL-MAML2 in secondary acute myelogenous leukemia and myelodysplastic syndrome with inv(11)(q21q23)
✍ Noriko Nemoto; Kazumi Suzukawa; Seiichi Shimizu; Atsushi Shinagawa; Naoko Takei; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 423 KB

## Abstract We have identified a novel fusion partner of __MLL__, namely the mastermind like 2 (__MAML____2__ gene), in secondary acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) with inv(11)(q21q23). RT‐PCR and sequencing revealed that exon 7 of __MLL__ was fused to exon 2 of __MAML