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Cryptic MLL-AF10 fusion caused by insertion of duplicated 5′ part of MLL into 10p12 in acute leukemia: a case report

✍ Scribed by Marie Jarosova; Sylvia Takacova; Milena Holzerova; Monika Priwitzerova; Martina Divoka; Ilona Lakoma; Vladimir Mihal; Karel Indrak; Vladimir Divoky


Book ID
113512705
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
432 KB
Volume
162
Category
Article
ISSN
0165-4608

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## Abstract The formation of a leukemogenic fusion product in hematopoietic malignancies is commonly achieved by chromosomal translocation. Alternate and cytogenetically undetectable mechanisms of fusion transcript generation have been documented for __BCR__–__AB1__, __AML1__–__ETO__, __PML__–__RAR