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Mixed Steroidal 1,2,4,5-Tetraoxanes: Antimalarial and Antimycobacterial Activity

✍ Scribed by Šolaja, Bogdan A.; Terzić, Nataša; Pocsfalvi, Gabriella; Gerena, Lucia; Tinant, Bernard; Opsenica, Dejan; Milhous, Wilbur K.


Book ID
121442499
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
83 KB
Volume
45
Category
Article
ISSN
0022-2623

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An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structures possess central tetraoxane rings with spiro-2,5-disubstituted cyclohexylidene substituents and 6-