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Steroidal geminal dihydroperoxides and 1,2,4,5-tetraoxanes: Structure determination and their antimalarial activity

✍ Scribed by Nina M. Todorović; Milutin Stefanovic; Bernard Tinant; Jean-Paul Declercq; Michael T. Makler; Bogdan A. S̆olaja


Book ID
117213815
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
800 KB
Volume
61
Category
Article
ISSN
0039-128X

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The structure and antimalarial activity
✍ Yuxiang Dong; Kevin J. McCullough; Sergio Wittlin; Jacques Chollet; Jonathan L. 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 266 KB

An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structures possess central tetraoxane rings with spiro-2,5-disubstituted cyclohexylidene substituents and 6-