𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Microwave-facilitated synthesis of [18F]-spiperone

✍ Scribed by D.-R. Hwang; S.M. Moerlein; C.S. Dence; M.J. Welch

Publisher
John Wiley and Sons
Year
1989
Tongue
French
Weight
96 KB
Volume
26
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis of no-carrier-added N-([18F]fl
Synthesis of no-carrier-added N-([18F]fluoroalkyl)spiperone derivatives
✍ Dae Yoon Chi; Michael R. Kilbourn; John A. Katzenellenbogen; James W. Brodack; M πŸ“‚ Article πŸ“… 1986 πŸ› Elsevier Science βš– 871 KB

3-N-([18F]fluoroalkyl)spiperone derivatives (2,3) can be prepared by N-alkylation of spiperone (1) with fluoroalkyl halides. The fluoroalkylating species 2-[18F]fluoroethyl bromide (7), 3-[18F]fluoropropyl bromide (8) and 4-[18F]fluorobutyl bromide (9) were prepared by [18F]fluoride ion displacement

Mechanistic approach of the nucleophilic
Mechanistic approach of the nucleophilic18F- exchange on 4β€²-NO2-spiperone using TBA18F or K2.2.2./K18F
✍ M. Gysemans; J. Mertens πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 French βš– 356 KB

## Abstract High yield single step preparation of 4′‐^18^F‐spiperone by ^18^F‐ for NO~2~ exchange in highly basic conditions fails when using 4′‐NO~2~‐spiperone as a precursor. This compound moreover inhibits radiofluorination of highly activated molecules in mentioned conditions. Inhibition is not

Microwave-assisted cyclocondensation of
Microwave-assisted cyclocondensation of 1,2-diaminobenzene with [4-18F]fluorobenzoic acid: microwave synthesis of 2-([4-18F]fluorophenyl) benzimidazole
✍ Gareth Getvoldsen; Anna Fredriksson; Nils Elander; Sharon Stone-Elander πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 99 KB

## Abstract The synthesis of 2‐([4‐^18^F]fluorophenyl)benzimidazole, which has potential to be used as a building block for many endogenous and pharmaceutical compounds, is reported. A range of solvents and catalysts as well as conventional and microwave heating have been investigated to optimise t